1Y91

Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.15 Å)

Cell axes53.37271.42372.004
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits25.00 - 2.15
the highest resolution shell value2.205 - 2.150
R-factor0.2009
R-work0.19612
the highest resolution shell value0.248
R-free0.29511
the highest resolution shell value0.381
RMSD bond length0.022
RMSD bond angle2.076

Data Collection Statistics

Resolution limits30.00 - 1.80
the highest resolution shell value -
Number of reflections24371
Rmerge_l_obs0.085
the highest resolution shell value0.380
Completeness92.9
Redundancy2.65
the highest resolution shell value1.92
I/sigma(I)1

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, HANGING DROP7.2293

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*