1Y8R
SUMO E1 ACTIVATING ENZYME SAE1-SAE2-SUMO1-MG-ATP COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Ubiquitin-like 1 activating enzyme E1A | polymer | 346 | 38499.8 | 2 | UniProt (Q9UBE0) Pfam (PF00899) | Homo sapiens (human) | SUMO-1 activating enzyme subunit 1 |
| 2 | B, E (B, E) | Ubiquitin-like 2 activating enzyme E1B | polymer | 640 | 71282.4 | 2 | UniProt (Q9UBT2) Pfam (PF00899) Pfam (PF14732) Pfam (PF16195) | Homo sapiens (human) | SUMO-1 activating enzyme subunit 2; Anthracycline-associated resistance ARX; HRIHFB2115 |
| 3 | C, F (C, F) | Ubiquitin-like protein SMT3C | polymer | 97 | 11149.5 | 2 | UniProt (P63165) Pfam (PF11976) | Homo sapiens (human) | Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein UBL1; Ubiquitin-related protein SUMO-1; GAP modifying protein 1; GMP1; Sentrin; OK/SW-cl.43 |
| 4 | G, J (B, E) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | H, K (B, E) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | I, L (B, E) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 7 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 640 (UniProt: Q9UBT2)
| PDB | External Database | Details |
|---|---|---|
| Ala 173 | Cys 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 241863.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1193.8 | |
| All* | Total formula weight | 243057.3 |
