1Y8N
Crystal structure of the PDK3-L2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | polymer | 419 | 48291.0 | 1 | UniProt (Q15120) Pfam (PF10436) Pfam (PF02518) In PDB | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 3 |
| 2 | B | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | polymer | 128 | 14192.1 | 1 | UniProt (P10515) Pfam (PF00364) In PDB | Homo sapiens (human) | E2, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, PDC-E2, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, M2 antigen complex 70 kDa subunit |
| 3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | B | DIHYDROLIPOIC ACID | non-polymer | 208.3 | 1 | Chemie (RED) | |||
| 5 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 9 - 406 (UniProt: Q15120)
B: 126 - 233 (UniProt: P10515)
| PDB | External Database | Details |
|---|---|---|
| Gly -12 | - | cloning artifact |
| Gly -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| His -9 | - | cloning artifact |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Met -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| Arg 0 | - | cloning artifact |
| Leu 1 | - | cloning artifact |
| Glu 2 | - | cloning artifact |
| Asn 3 | - | cloning artifact |
| Leu 4 | - | cloning artifact |
| Tyr 5 | - | cloning artifact |
| Phe 6 | - | cloning artifact |
| Gln 7 | - | cloning artifact |
| Gly 8 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | cloning artifact |
| Gly 107 | - | cloning artifact |
| Ser 108 | - | cloning artifact |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| His 114 | - | expression tag |
| Gly 115 | - | cloning artifact |
| Met 116 | - | cloning artifact |
| Ala 117 | - | cloning artifact |
| Arg 118 | - | cloning artifact |
| Leu 119 | - | cloning artifact |
| Glu 120 | - | cloning artifact |
| Asn 121 | - | cloning artifact |
| Leu 122 | - | cloning artifact |
| Tyr 123 | - | cloning artifact |
| Phe 124 | - | cloning artifact |
| Gln 125 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62483.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 247.4 | |
| All* | Total formula weight | 62730.5 |
