1Y57
Structure of unphosphorylated c-Src in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 452 | 51629.6 | 1 | UniProt (P12931) Pfam (PF00018) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | p60-Src, c-Src |
| 2 | B, C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G (A) | 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE | non-polymer | 479.6 | 1 | Chemie (MPZ) | |||
| 4 | H (A) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A: 83 - 533 (UniProt: P12931)
| PDB | External Database | Details |
|---|---|---|
| Met 82 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51629.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 959.9 | |
| All* | Total formula weight | 52589.5 |
