1Y0V

Crystal structure of anthrax edema factor (EF) in complex with calmodulin and pyrophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Calmodulin-sensitive adenylate cyclase	polymer	777	90128.9	6	UniProt (P40136) Pfam (PF07737) Pfam (PF03497) Pfam (PF20850) In PDB	Bacillus anthracis	ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component
2	H, I, J, K, L...	Calmodulin	polymer	146	16436.1	6	UniProt (P62155) Pfam (PF13499) UniProt (by SIFTS) (P0DP33) In PDB	Xenopus laevis (African clawed frog)	CaM
3	A, B, C, D, E...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	A, B, C, D, E...	PYROPHOSPHATE 2-	non-polymer		176.0	6	Chemie (POP)
5	H, I, J, K, L...	CALCIUM ION	non-polymer		40.1	18	Chemie (CA)

Sequence modifications

A, B, C, D, E, F: 33 - 800 (UniProt: P40136)

PDB	External Database	Details
Met 24	-	cloning artifact
His 25	-	cloning artifact
His 26	-	cloning artifact
His 27	-	cloning artifact
His 28	-	cloning artifact
His 29	-	cloning artifact
His 30	-	cloning artifact
Ala 31	-	cloning artifact
Ala 32	-	cloning artifact

H, I, J, K, L, M: 5 - 148 (UniProt: P62155)

PDB	External Database	Details
Ala 3	-	cloning artifact
Ala 4	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	639389.7
Non-Polymers*	Number of molecules	30
	Total formula weight	1923.0
All*	Total formula weight	641312.7

*Water molecules are not included.