1XSL
Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (B, F, J, N) | 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3' | polymer | 11 | 3344.2 | 4 | |||
| 2 | B, E, H, K (C, G, K, O) | 5'-D(*GP*TP*GP*CP*GP*C)-3' | polymer | 6 | 1825.2 | 4 | |||
| 3 | C, F, I, L (D, H, L, P) | 5'-D(P*GP*CP*CP*G)-3' | polymer | 4 | 1191.8 | 4 | |||
| 4 | M, N, O, P (A, E, I, M) | DNA polymerase lambda | polymer | 335 | 37479.8 | 4 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda, DNA polymerase beta-2, Pol beta2 |
| 5 | Q, S, T (B, F, H) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | R (D) | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 7 | U, V, W, X, Y... (J, N, A, E, I...) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 8 | AA, BA, CA, DA, EA... (B, C, D, F, G...) | water | water | 18.0 | 843 | Chemie (HOH) |
Sequence modifications
A, E, I, M: 242 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Met 241 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 175363.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 347.8 | |
| All* | Total formula weight | 175711.7 |
