1XR2

Crystal Structure of oxidized T. maritima Cobalamin-Independent Methionine Synthase complexed with Methyltetrahydrofolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	polymer	766	89339.2	2	UniProt (Q9X112) Pfam (PF08267) Pfam (PF01717) In PDB	Thermotoga maritima	Methionine synthase, vitamin-B12 independent isozyme, Cobalamin-independent methionine synthase
2	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A, B	5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID	non-polymer		459.5	2	Chemie (C2F)
4	A, B	MESO-ERYTHRITOL	non-polymer		122.1	2	Chemie (MRY)
5		water	water		18.0	238	Chemie (HOH)

Sequence modifications

A, B: 2 - 734 (UniProt: Q9X112)

PDB	External Database	Details
Met -31	-	EXPRESSION TAG
His -30	-	EXPRESSION TAG
His -29	-	EXPRESSION TAG
His -28	-	EXPRESSION TAG
His -27	-	EXPRESSION TAG
His -26	-	EXPRESSION TAG
His -25	-	EXPRESSION TAG
Gly -24	-	EXPRESSION TAG
Lys -23	-	EXPRESSION TAG
Pro -22	-	EXPRESSION TAG
Ile -21	-	EXPRESSION TAG
Pro -20	-	EXPRESSION TAG
Asn -19	-	EXPRESSION TAG
Pro -18	-	EXPRESSION TAG
Leu -17	-	EXPRESSION TAG
Leu -16	-	EXPRESSION TAG
Gly -15	-	EXPRESSION TAG
Leu -14	-	EXPRESSION TAG
Asp -13	-	EXPRESSION TAG
Ser -12	-	EXPRESSION TAG
Thr -11	-	EXPRESSION TAG
Glu -10	-	EXPRESSION TAG
Asn -9	-	EXPRESSION TAG
Leu -8	-	EXPRESSION TAG
Tyr -7	-	EXPRESSION TAG
Phe -6	-	EXPRESSION TAG
Gln -5	-	EXPRESSION TAG
Gly -4	-	EXPRESSION TAG
Ile -3	-	EXPRESSION TAG
Asp -2	-	EXPRESSION TAG
Pro -1	-	EXPRESSION TAG
Phe 0	-	EXPRESSION TAG
Thr 1	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	178678.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1355.3
All*	Total formula weight	180033.7

*Water molecules are not included.