1XQL
Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Alanine racemase | polymer | 388 | 43679.1 | 2 | UniProt (P10724) Pfam (PF01168) Pfam (PF00842) In PDB | Geobacillus stearothermophilus | |
2 | A, B | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE | non-polymer | 248.2 | 2 | Chemie (PMP) | |||
3 | A, B | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 331.2 | 2 | Chemie (PMH) | |||
4 | A, B | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
5 | A, B | (R)-4-AMINO-ISOXAZOLIDIN-3-ONE | non-polymer | 102.1 | 2 | Chemie (4AX) | |||
6 | A, B | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
7 | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 382 (UniProt: P10724)
PDB | External Database | Details |
---|---|---|
Kcx 129 | Lys 129 | modified residue |
Phe 265 | Tyr 265 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 87358.1 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1977.4 | |
All* | Total formula weight | 89335.5 |