1XPG
Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Methyltetrahydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | polymer | 765 | 89991.3 | 2 | UniProt (Q9X112) Pfam (PF08267) Pfam (PF01717) | Thermotoga maritima | Methionine synthase, vitamin-B12 independent isozyme, Cobalamin-independent methionine synthase |
| 2 | C, D, H (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, K (A, B) | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID | non-polymer | 459.5 | 2 | Chemie (C2F) | |||
| 5 | G, J (A, B) | MESO-ERYTHRITOL | non-polymer | 122.1 | 2 | Chemie (MRY) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 732 (UniProt: Q9X112)
| PDB | External Database | Details |
|---|---|---|
| Met -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Lys -23 | - | expression tag |
| Pro -22 | - | expression tag |
| Ile -21 | - | expression tag |
| Pro -20 | - | expression tag |
| Asn -19 | - | expression tag |
| Pro -18 | - | expression tag |
| Leu -17 | - | expression tag |
| Leu -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Leu -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Asn -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ile -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Thr 1 | - | expression tag |
| Mse 38 | Met 38 | modified residue |
| Mse 43 | Met 43 | modified residue |
| Mse 45 | Met 45 | modified residue |
| Mse 73 | Met 73 | modified residue |
| Mse 93 | Met 93 | modified residue |
| Mse 102 | Met 102 | modified residue |
| Mse 170 | Met 170 | modified residue |
| Mse 344 | Met 344 | modified residue |
| Mse 421 | Met 421 | modified residue |
| Mse 468 | Met 468 | modified residue |
| Mse 510 | Met 510 | modified residue |
| Mse 529 | Met 529 | modified residue |
| Mse 537 | Met 537 | modified residue |
| Mse 619 | Met 619 | modified residue |
| Mse 682 | Met 682 | modified residue |
| Mse 721 | Met 721 | modified residue |
| Mse 728 | Met 728 | modified residue |
| Ala 733 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 179982.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1582.2 | |
| All* | Total formula weight | 181564.8 |
