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CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH (3A-ALPHA-,4-ALPHA 7-ALPHA-,7A-ALPHA-)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 260 | 30252.4 | 1 | UniProt (P15207) Pfam (PF00104) | Rattus norvegicus (Norway rat) | Dihydrotestosterone receptor |
| 2 | B (A) | REL-(3AR,4S,7R,7AS)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE | non-polymer | 350.4 | 1 | Chemie (HYQ) | |||
| 3 | C (A) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 664 - 919 (UniProt: P15207)
| PDB | External Database | Details |
|---|---|---|
| Gly 660 | - | cloning artifact |
| Ser 661 | - | cloning artifact |
| His 662 | - | cloning artifact |
| Met 663 | - | cloning artifact |
| Ala 877 | Thr 860 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30252.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 350.4 | |
| All* | Total formula weight | 30602.8 |
