1XKP

Crystal structure of the virulence factor YopN in complex with its heterodimeric chaperone SycN-YscB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	putative membrane-bound Yop targeting protein YopN	polymer	246	27741.4	1	GenBank (3822072) Pfam (PF07201) UniProt (by SIFTS) (P68640)	Yersinia pestis
2	B (B)	Chaperone protein sycN	polymer	124	13771.0	1	UniProt (P61380) Pfam (PF21665)	Yersinia pestis
3	C (C)	Chaperone protein yscB	polymer	143	16392.2	1	UniProt (Q56973) Pfam (PF05932)	Yersinia pestis	Yop proteins translocation protein B
4	D, E, F (A, B, C)	water	water		18.0	179	Chemie (HOH)

Sequence modifications

A: 32 - 277 (GenBank: 3822072)

PDB	External Database	Details
Dmg 32	Gly 32	modified residue
Mly 64	Lys 64	modified residue
Mly 70	Lys 70	modified residue
Mly 72	Lys 72	modified residue
Mly 93	Lys 93	modified residue
Mly 100	Lys 100	modified residue
Mly 122	Lys 122	modified residue
Mly 128	Lys 128	modified residue
Mly 137	Lys 137	modified residue
Mly 147	Lys 147	modified residue
Mly 221	Lys 221	modified residue
Mly 237	Lys 237	modified residue
Mly 254	Lys 254	modified residue
Mly 264	Lys 264	modified residue
Mly 266	Lys 266	modified residue
Mly 276	Lys 276	modified residue

B: 1 - 124 (UniProt: P61380)

PDB	External Database	Details
Mly 65	Lys 65	modified residue
Mly 74	Lys 74	modified residue
Pro 123	Ser 123	engineered mutation

C: 1 - 137 (UniProt: Q56973)

PDB	External Database	Details
Mly 6	Lys 6	modified residue
Mly 15	Lys 15	modified residue
Mly 21	Lys 21	modified residue
Mly 31	Lys 31	modified residue
Mly 113	Lys 113	modified residue
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	57904.6
All*	Total formula weight	57904.6

*Water molecules are not included.