1XKG

Crystal structure of the major house dust mite allergen Der p 1 in its pro form at 1.61 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Major mite fecal allergen Der p 1	polymer	312	35424.1	1	UniProt (P08176) Pfam (PF00112) In PDB	Dermatophagoides pteronyssinus (European house dust mite)	Der p I
2	A	YTTRIUM (III) ION	non-polymer		88.9	1	Chemie (YT3)
3	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5		water	water		18.0	312	Chemie (HOH)

Sequence modifications

A: 1 - 302 (UniProt: P08176)

PDB	External Database	Details
Ala 114	Cys 132	engineered mutation
Asp 132	Asn 150	engineered mutation
Ala 204	Val 222	engineered mutation
Gly 303	-	expression tag
Gln 304	-	expression tag
Thr 305	-	expression tag
Gly 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35424.1
Non-Polymers*	Number of molecules	5
	Total formula weight	465.2
All*	Total formula weight	35889.4

*Water molecules are not included.