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1XKG

Crystal structure of the major house dust mite allergen Der p 1 in its pro form at 1.61 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Major mite fecal allergen Der p 1polymer31235424.11UniProt (P08176)
Pfam (PF00112)
Dermatophagoides pteronyssinus (European house dust mite)Der p I
2B
(A)
YTTRIUM (III) IONnon-polymer88.91Chemie (YT3)
3C, D
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
4E, F
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5G
(A)
waterwater18.0312Chemie (HOH)
Sequence modifications
A: 1 - 302 (UniProt: P08176)
PDBExternal DatabaseDetails
Ala 114Cys 132engineered mutation
Asp 132Asn 150engineered mutation
Ala 204Val 222engineered mutation
Gly 303-expression tag
Gln 304-expression tag
Thr 305-expression tag
Gly 306-expression tag
His 307-expression tag
His 308-expression tag
His 309-expression tag
His 310-expression tag
His 311-expression tag
His 312-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35424.1
Non-Polymers*Number of molecules5
Total formula weight465.2
All*Total formula weight35889.4
*Water molecules are not included.

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PDB entries from 2025-07-09

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