1XG4
Crystal Structure of the C123S 2-Methylisocitrate Lyase Mutant from Escherichia coli in complex with the inhibitor isocitrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Probable methylisocitrate lyase | polymer | 295 | 32022.4 | 4 | UniProt (P77541) Pfam (PF13714) | Escherichia coli | 2-methylisocitrate lyase |
| 2 | E, G, I (A, B, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | F, H, J (A, B, D) | ISOCITRIC ACID | non-polymer | 192.1 | 3 | Chemie (ICT) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 982 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 296 (UniProt: P77541)
| PDB | External Database | Details |
|---|---|---|
| Ser 123 | Cys 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 128089.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 649.3 | |
| All* | Total formula weight | 128738.7 |
