1XFV
Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Calmodulin-sensitive adenylate cyclase | polymer | 777 | 90128.9 | 6 | UniProt (P40136) Pfam (PF07737) Pfam (PF03497) Pfam (PF20850) | Bacillus anthracis | ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component |
| 2 | G, H, I, J, K... (O, P, Q, R, S...) | Calmodulin 2 | polymer | 149 | 16851.6 | 6 | UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (human) | |
| 3 | BA, CA, M, N, P... (F, A, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 4 | AA, DA, O, R, U... (E, F, A, B, C...) | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE | non-polymer | 491.2 | 6 | Chemie (3AT) | |||
| 5 | EA, FA, GA, HA, IA... (O, P, Q, R, S...) | CALCIUM ION | non-polymer | 40.1 | 18 | Chemie (CA) | |||
| 6 | AB, BB, WA, XA, YA... (E, F, A, B, C...) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 33 - 800 (UniProt: P40136)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | initiating methionine |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| Ala 31 | - | cloning artifact |
| Ala 32 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 641882.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 3960.2 | |
| All* | Total formula weight | 645842.9 |
