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1X97

Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat, 2S4S)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAldose Reductasepolymer31635898.31UniProt (P15121)
Pfam (PF00248)
In PDB
Homo sapiens (human)
2ANADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3A(2R,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONEnon-polymer279.21Chemie (FIR)
4waterwater18.0469Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35898.3
Non-Polymers*Number of molecules2
Total formula weight1022.6
All*Total formula weight36921.0
*Water molecules are not included.

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