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1X81

Farnesyl transferase structure of Jansen compound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunitpolymer31538028.81UniProt (Q04631)
Pfam (PF01239)
Rattus norvegicus (Norway rat)CAAX farnesyltransferase alpha subunit, Ras proteins prenyltransferase alpha, FTase-alpha, Type I protein geranyl-geranyltransferase alpha subunit, GGTase-I-alpha
2B
(B)
Protein farnesyltransferase beta subunitpolymer39744478.81UniProt (Q02293)
Pfam (PF00432)
Rattus norvegicus (Norway rat)CAAX farnesyltransferase beta subunit, RAS proteins prenyltransferase beta, FTase-beta
3C
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(B)
6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONEnon-polymer489.41Chemie (JAN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82507.6
Non-Polymers*Number of molecules2
Total formula weight554.8
All*Total formula weight83062.4
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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