1X0J
Crystal structure analysis of the N-terminal bromodomain of human Brd2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Bromodomain-containing protein 2 | polymer | 122 | 14800.1 | 3 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (human) | Brd2, RING3 protein, O27.1.1 |
| 2 | A, B, C | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 3 | Chemie (DTT) | |||
| 3 | C | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 4 | water | water | 18.0 | 352 | Chemie (HOH) |
Sequence modifications
A, B, C: 73 - 194 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Mse 87 | Met 87 | MODIFIED RESIDUE |
| Mse 121 | Met 121 | MODIFIED RESIDUE |
| Mse 123 | Met 123 | MODIFIED RESIDUE |
| Mse 142 | Met 142 | MODIFIED RESIDUE |
| Mse 148 | Met 148 | MODIFIED RESIDUE |
| Mse 165 | Met 165 | MODIFIED RESIDUE |
| Mse 180 | Met 180 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44400.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 658.0 | |
| All* | Total formula weight | 45058.4 |
