1X0J
Crystal structure analysis of the N-terminal bromodomain of human Brd2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DTT A 1301 |
| Chain | Residue |
| A | VAL103 |
| A | LEU108 |
| A | TYR113 |
| A | ASN156 |
| A | ILE162 |
| A | HOH1303 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DTT B 1302 |
| Chain | Residue |
| B | ILE162 |
| B | HOH1306 |
| B | HOH1345 |
| B | HOH1398 |
| B | LEU108 |
| B | TYR113 |
| B | ASN156 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DTT C 1303 |
| Chain | Residue |
| B | GLN80 |
| C | PRO98 |
| C | VAL103 |
| C | LEU108 |
| C | ASN156 |
| C | ILE162 |
| C | HOH1403 |
| C | HOH1417 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES C 1401 |
| Chain | Residue |
| A | TRP97 |
| A | ARG100 |
| C | ARG128 |
| C | ASN132 |
| C | TYR134 |
| C | HOH1484 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37731000","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SB6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20048151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2DVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DVS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
