1WYG
Crystal Structure of a Rat Xanthine Dehydrogenase Triple Mutant (C535A, C992R and C1324S)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Xanthine dehydrogenase/oxidase | polymer | 1331 | 146420.3 | 1 | UniProt (P22985) Pfam (PF00111) Pfam (PF01799) Pfam (PF00941) Pfam (PF03450) Pfam (PF01315) Pfam (PF02738) Pfam (PF20256) | Rattus norvegicus (Norway rat) | |
| 2 | B, C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | F, G (A) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 5 | H (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 6 | I (A) | 2-HYDROXYBENZOIC ACID | non-polymer | 138.1 | 1 | Chemie (SAL) | |||
| 7 | J (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 8 | K (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 2 - 1331 (UniProt: P22985)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 535 | Cys 534 | engineered mutation |
| Arg 992 | Cys 991 | engineered mutation |
| Ser 1324 | Cys 1323 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 146420.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1660.4 | |
| All* | Total formula weight | 148080.6 |
