1WTG

Human Factor Viia-Tissue Factor Complexed with ethylsulfonamide-D-biphenylalanine-Gln-p-aminobenzamidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L	Coagulation factor VII	polymer	152	17487.1	1	UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) In PDB	Homo sapiens (human)	Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa
2	H	Coagulation factor VII	polymer	254	28103.3	1	UniProt (P08709) Pfam (PF00089) In PDB	Homo sapiens (human)	Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa
3	T	Tissue factor	polymer	218	24697.4	1	UniProt (P13726) Pfam (PF01108) Pfam (PF09294) In PDB	Homo sapiens (human)	TF, Coagulation factor III, Thromboplastin, CD142 antigen
4	L	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
5	L	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
6	L, H	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)
7	H	2-(3-BIPHENYL-4-YL-2-ETHANESULFONYLAMINO-PROPIONYLAMINO)-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE)	non-polymer		592.7	1	Chemie (3BP)
8		water	water		18.0	511	Chemie (HOH)

Sequence modifications

L: 1 - 152 (UniProt: P08709)

PDB	External Database	Details
Cgu 6	Glu 66	modified residue
Cgu 7	Glu 67	modified residue
Cgu 14	Glu 74	modified residue
Cgu 16	Glu 76	modified residue
Cgu 19	Glu 79	modified residue
Cgu 20	Glu 80	modified residue
Cgu 25	Glu 85	modified residue
Cgu 26	Glu 86	modified residue
Cgu 29	Glu 89	modified residue
Cgu 35	Glu 95	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70287.7
Non-Polymers*	Number of molecules	12
	Total formula weight	1297.7
All*	Total formula weight	71585.5

*Water molecules are not included.