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1WSI

Crystal structure of E.coli RNase HI active site mutant (E48A/K87A/D134N)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Ribonuclease HIpolymer15517505.94UniProt (P0A7Y4)
Pfam (PF00075)
Escherichia coliRNase HI, Ribonuclease H, RNase H
2E, F, G, H
(A, B, C, D)
waterwater18.0316Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 155 (UniProt: P0A7Y4)
PDBExternal DatabaseDetails
Ala 48Glu 48engineered mutation
Ala 87Lys 87engineered mutation
Asn 134Asp 134engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight70023.5
All*Total formula weight70023.5
*Water molecules are not included.

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PDB entries from 2025-11-19

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