1WRL
Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine (monoclinic crystal form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Troponin C, slow skeletal and cardiac muscles | polymer | 88 | 9951.1 | 6 | UniProt (P63316) Pfam (PF13833) | Homo sapiens (human) | TN-C |
| 2 | G, J, M, P, S... (A, B, C, D, E...) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | H, I, K, L, N... (A, B, C, D, E...) | 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE | non-polymer | 407.5 | 12 | Chemie (TFP) | |||
| 4 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 88 (UniProt: P63316)
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | Cys 35 | engineered mutation |
| Ser 84 | Cys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 59706.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 5130.4 | |
| All* | Total formula weight | 64837.0 |
