1WQ6
The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AML1-ETO | polymer | 72 | 9153.7 | 2 | UniProt (Q06455) Pfam (PF08788) | Homo sapiens (human) | Protein CBFA2T1, MTG8 protein, ETO protein, Eigth twenty one protein, Cyclin D related protein, Zinc finger MYND domain containing protein 2 |
| 2 | C, D (A, B) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 72 (UniProt: Q06455)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | cloning artifact |
| Mse 2 | - | cloning artifact |
| Ala 3 | - | cloning artifact |
| Mse 9 | Met 340 | modified residue |
| Mse 34 | Met 365 | modified residue |
| Mse 36 | Met 367 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18307.5 | |
| All* | Total formula weight | 18307.5 |
