1WKW
Crystal structure of the ternary complex of eIF4E-m7GpppA-4EBP1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Eukaryotic translation initiation factor 4E | polymer | 191 | 22288.3 | 1 | UniProt (P06730) Pfam (PF01652) | Homo sapiens (human) | eIF4E, eIF-4E, mRNA cap-binding protein, eIF-4F 25 kDa subunit |
| 2 | B (B) | Eukaryotic translation initiation factor 4E binding protein 1 | polymer | 20 | 2357.8 | 1 | UniProt (Q13541) | Homo sapiens (human) | 4E binding protein 1, 4E-BP1, eIF4E-binding protein 1, PHAS-I |
| 3 | C (A) | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 1 | Chemie (GTA) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24646.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 787.4 | |
| All* | Total formula weight | 25433.4 |
