1WCX
Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uroporphyrinogen III Synthase | polymer | 261 | 28729.8 | 1 | UniProt (Q5SKH2) Pfam (PF02602) | Thermus thermophilus | |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
A: 10 - 261 (UniProt: Q5SKH2)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | cloning artifact |
| Arg 2 | - | cloning artifact |
| Arg 3 | - | cloning artifact |
| Leu 4 | - | cloning artifact |
| Glu 5 | - | cloning artifact |
| Glu 6 | - | cloning artifact |
| Asp 7 | - | cloning artifact |
| Ala 8 | - | cloning artifact |
| Val 9 | - | cloning artifact |
| Mse 75 | Leu 67 | engineered mutation |
| Mse 161 | Met 153 | modified residue |
| Mse 193 | Ile 185 | engineered mutation |
| Mse 248 | Leu 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28729.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 28821.9 |
