1WCS
A mutant of Trypanosoma rangeli sialidase displaying trans-sialidase activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SIALIDASE | polymer | 641 | 70071.9 | 1 | UniProt (O44049) Pfam (PF13859) Pfam (PF22925) | TRYPANOSOMA RANGELI |
Sequence modifications
A: 1 - 1 (PDB: 1WCS)
A: 2 - 2 (PDB: 1WCS)
A: 3 - 3 (PDB: 1WCS)
A: 4 - 641 (UniProt: O44049)
A: 2 - 2 (PDB: 1WCS)
A: 3 - 3 (PDB: 1WCS)
A: 4 - 641 (UniProt: O44049)
| PDB | External Database | Details |
|---|---|---|
| Ile 53 | Thr 72 | conflict |
| Val 99 | Met 118 | engineered mutation |
| Pro 101 | Ala 120 | engineered mutation |
| Tyr 123 | Ser 142 | engineered mutation |
| Val 180 | Ile 199 | conflict |
| Ala 189 | Ile 208 | conflict |
| Tyr 252 | Gly 271 | engineered mutation |
| Pro 287 | Gln 306 | engineered mutation |
| Leu 375 | Phe 394 | conflict |
| Ala 413 | Gly 432 | conflict |
| Val 609 | Ile 628 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70071.9 | |
| All* | Total formula weight | 70071.9 |
