1WCQ
Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | SIALIDASE | polymer | 601 | 64282.6 | 3 | UniProt (Q02834) Pfam (PF13088) Pfam (PF10633) Pfam (PF00754) | MICROMONOSPORA VIRIDIFACIENS | NEURAMINIDASE |
| 2 | D, H, M (A, B, C) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | E, F, I, J, K... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | G, L, P (A, B, C) | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 3 | Chemie (DAN) | |||
| 5 | Q, R, S (A, B, C) | water | water | 18.0 | 1078 | Chemie (HOH) |
Sequence modifications
A, B, C: 47 - 647 (UniProt: Q02834)
| PDB | External Database | Details |
|---|---|---|
| Phe 370 | Tyr 370 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 192847.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1587.4 | |
| All* | Total formula weight | 194435.3 |
