1WBN

fragment based p38 inhibitors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MITOGEN-ACTIVATED PROTEIN KINASE 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	MITOGEN-ACTIVATED PROTEIN KINASE P38ALPHA, MAP KINASE P38ALPHA, CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG BINDING PROTEIN, CSAID BINDING PROTEIN, CSBP, MAX-INTERACTING PROTEIN 2, MAP KINASE MXI2, SAPK2A
2	A	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	non-polymer		399.9	1	Chemie (L09)
3		water	water		18.0	552	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 1WBN)
A: 2 - 360 (UniProt: Q16539)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	1
	Total formula weight	399.9
All*	Total formula weight	41743.1

*Water molecules are not included.