1W6Q

X-RAY CRYSTAL STRUCTURE OF R111H HUMAN GALECTIN-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	GALECTIN-1	polymer	134	14596.4	1	UniProt (P09382) Pfam (PF00337) In PDB	HOMO SAPIENS (HUMAN)	BETA-GALACTOSIDE-BINDING LECTIN L-14-I, HPL, LACTOSE-BINDING LECTIN 1, S-LAC LECTIN 1, GALAPTIN, HBL
2	B	GALECTIN-1	polymer	134	14580.4	1	UniProt (P09382) Pfam (PF00337) In PDB	HOMO SAPIENS (HUMAN)	BETA-GALACTOSIDE-BINDING LECTIN L-14-I, HPL, LACTOSE-BINDING LECTIN 1, S-LAC LECTIN 1, GALAPTIN, HBL
3	A, B	BETA-MERCAPTOETHANOL	non-polymer		78.1	6	Chemie (BME)
4		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 1001 - 1134 (UniProt: P09382)

PDB	External Database	Details
His 1111	Arg 111	engineered mutation

B: 2001 - 2134 (UniProt: P09382)

PDB	External Database	Details
His 2111	Arg 111	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29176.9
Non-Polymers*	Number of molecules	6
	Total formula weight	468.8
All*	Total formula weight	29645.7

*Water molecules are not included.