1W2C
Human Inositol (1,4,5) trisphosphate 3-kinase complexed with Mn2+/AMPPNP/Ins(1,4,5)P3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INOSITOL-TRISPHOSPHATE 3-KINASE A | polymer | 265 | 30425.7 | 2 | UniProt (P23677) Pfam (PF03770) | HOMO SAPIENS (HUMAN) | INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE, IP3-3K |
| 2 | C, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | D, I (A, B) | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE | non-polymer | 420.1 | 2 | Chemie (I3P) | |||
| 4 | E, J (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | F, G, K (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60851.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2250.6 | |
| All* | Total formula weight | 63101.9 |
