1W1G

Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain bound to DiC4-phosphatidylinositol (3,4,5)-trisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1	polymer	151	17816.2	1	UniProt (O15530) Pfam (PF14593)	HOMO SAPIENS (HUMAN)	HPDK1
2	B (A)	(2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE	non-polymer		716.4	1	Chemie (4PT)
3	C (A)	water	water		18.0	163	Chemie (HOH)

Sequence modifications

A: 406 - 408 (PDB: 1W1G)
A: 409 - 556 (UniProt: O15530)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17816.2
Non-Polymers*	Number of molecules	1
	Total formula weight	716.4
All*	Total formula weight	18532.5

*Water molecules are not included.