1W1G
Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain bound to DiC4-phosphatidylinositol (3,4,5)-trisphosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 4PT A1550 |
| Chain | Residue |
| A | HIS417 |
| A | HOH2029 |
| A | HOH2084 |
| A | HOH2155 |
| A | HOH2156 |
| A | HOH2157 |
| A | LEU419 |
| A | LYS465 |
| A | LYS467 |
| A | ARG472 |
| A | ARG474 |
| A | TYR486 |
| A | LYS495 |
| A | ARG521 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:10455013 |
| Chain | Residue | Details |
| A | SER410 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKC/PRKCQ => ECO:0000250|UniProtKB:Q9Z2A0 |
| Chain | Residue | Details |
| A | SER501 | |
| A | SER529 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by autocatalysis => ECO:0000269|PubMed:16780920 |
| Chain | Residue | Details |
| A | THR513 |
