1W1G
Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain bound to DiC4-phosphatidylinositol (3,4,5)-trisphosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 4PT A1550 |
| Chain | Residue |
| A | HIS417 |
| A | HOH2029 |
| A | HOH2084 |
| A | HOH2155 |
| A | HOH2156 |
| A | HOH2157 |
| A | LEU419 |
| A | LYS465 |
| A | LYS467 |
| A | ARG472 |
| A | ARG474 |
| A | TYR486 |
| A | LYS495 |
| A | ARG521 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 91 |
| Details | Domain: {"description":"PH"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"10455013","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC/PRKCQ","evidences":[{"source":"UniProtKB","id":"Q9Z2A0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"16780920","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
