1VZQ
Complex of thrombin with designed inhibitor 7165
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN HEAVY | polymer | 250 | 28750.1 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 2 | B (I) | HIRUDIN VARIANT-2 | polymer | 11 | 1411.5 | 1 | UniProt (P09945) UniProt (by SIFTS) (P28504) | HIRUDO MEDICINALIS | HIRUDIN IIB |
| 3 | C (L) | THROMBIN LIGHT | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 4 | D (H) | 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE | non-polymer | 448.5 | 1 | Chemie (SHY) | |||
| 5 | E (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G, H, I (H, I, L) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33350.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 511.5 | |
| All* | Total formula weight | 33861.7 |
