1VZD
L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH FDUMP AND CB3717
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | THYMIDYLATE SYNTHASE | polymer | 316 | 36585.5 | 1 | UniProt (P00469) Pfam (PF00303) In PDB | Lactobacillus casei | TS, LCTS |
2 | A | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 326.2 | 1 | Chemie (UFP) | |||
3 | A | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 1 | Chemie (CB3) | |||
4 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 1 - 316 (UniProt: P00469)
PDB | External Database | Details |
---|---|---|
Gln 60 | Glu 60 | engineered mutation |
Ala 111 | Asp 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36585.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 803.6 | |
All* | Total formula weight | 37389.1 |