1VYQ
Novel inhibitors of Plasmodium Falciparum dUTPase provide a platform for anti-malarial drug design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | polymer | 173 | 19603.2 | 3 | UniProt (Q8II92) Pfam (PF00692) | PLASMODIUM FALCIPARUM | DUTP PYROPHOSPHATASE |
| 2 | D, E, F (A, B, C) | 2,3-DEOXY-3-FLUORO-5-O-TRITYLURIDINE | non-polymer | 472.5 | 3 | Chemie (DUX) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58809.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1417.5 | |
| All* | Total formula weight | 60227.0 |
