1VJB

crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Estrogen-related receptor gamma	polymer	251	28386.9	2	UniProt (P62509) Pfam (PF00104) UniProt (by SIFTS) (P62508) In PDB	Mus musculus (Mouse)	Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3
2	A, B	4-HYDROXYTAMOXIFEN	non-polymer		387.5	2	Chemie (OHT)

Sequence modifications

A, B: 229 - 458 (UniProt: P62509)

PDB	External Database	Details
Met 208	-	initiating methionine
Gly 209	-	expression tag
Ser 210	-	expression tag
Ser 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
Ser 218	-	expression tag
Ser 219	-	expression tag
Gly 220	-	expression tag
Leu 221	-	expression tag
Val 222	-	expression tag
Pro 223	-	expression tag
Arg 224	-	expression tag
Gly 225	-	expression tag
Ser 226	-	expression tag
His 227	-	expression tag
Met 228	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56773.9
Non-Polymers*	Number of molecules	2
	Total formula weight	775.0
All*	Total formula weight	57548.9

*Water molecules are not included.