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1VGA

Structures of unligated and inhibitor complexes of W168F mutant of Triosephosphate Isomerase from Plasmodium falciparum

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Triosephosphate isomerasepolymer24827958.74UniProt (Q07412)
Pfam (PF00121)
Plasmodium falciparum (malaria parasite P. falciparum)TIM
2E, F, G, H
(A, B, C, D)
waterwater18.0558Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 248 (UniProt: Q07412)
PDBExternal DatabaseDetails
Val 163Ala 163engineered mutation
Phe 168Trp 168engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight111834.8
All*Total formula weight111834.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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