1VG0
The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rab proteins geranylgeranyltransferase component A 1 | polymer | 650 | 72622.2 | 1 | UniProt (P37727) Pfam (PF00996) Pfam (PF22603) | Rattus norvegicus (Norway rat) | Rab escort protein 1, REP-1 |
| 2 | B (B) | Ras-related protein Rab-7 | polymer | 207 | 23530.7 | 1 | UniProt (P09527) Pfam (PF00071) | Rattus norvegicus (Norway rat) | RAS-related protein P23, RAS-related protein BRL-RAS |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 4 | D (A) | GERAN-8-YL GERAN | non-polymer | 274.5 | 1 | Chemie (GER) | |||
| 5 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | G (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 8 | H, I (A, B) | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A: 1 - 650 (UniProt: P37727)
| PDB | External Database | Details |
|---|---|---|
| Lys 231 | Gln 231 | engineered mutation |
| Arg 462 | Lys 462 | engineered mutation |
| Thr 473 | Ala 473 | engineered mutation |
| Ala 483 | Gly 483 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96153.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 971.7 | |
| All* | Total formula weight | 97124.6 |
