1V7P

Structure of EMS16-alpha2-I domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	EMS16 A chain	polymer	134	15889.5	1	UniProt (Q7T2Q1) Pfam (PF00059) In PDB	Echis multisquamatus	EMS16 subunit A
2	B	EMS16 B chain	polymer	128	15121.4	1	UniProt (Q7T2Q0) Pfam (PF00059) In PDB	Echis multisquamatus	EMS16 subunit B
3	C	Integrin alpha-2	polymer	200	21878.7	1	UniProt (P17301) Pfam (PF00092) In PDB	Homo sapiens (human)	alpha2-I, Platelet membrane glycoprotein Ia, GPIa, Collagen receptor, VLA-2 alpha chain, CD49b
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
7	C	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
8		water	water		18.0	463	Chemie (HOH)

Sequence modifications

B: 1 - 128 (UniProt: Q7T2Q0)

PDB	External Database	Details
Ser 43	Gly 69	engineered mutation

C: 138 - 337 (UniProt: P17301)

PDB	External Database	Details
Gly 138	Gln 167	engineered mutation
Ser 139	Pro 168	engineered mutation
Ser 140	Cys 169	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	52889.6
Non-Polymers*	Number of molecules	4
	Total formula weight	406.6
All*	Total formula weight	53296.2

*Water molecules are not included.