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1UZ4

Common inhibition of beta-glucosidase and beta-mannosidase by isofagomine lactam reflects different conformational intineraries for glucoside and mannoside hydrolysis

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MAN5Apolymer44050230.71UniProt (Q6QT42)CELLVIBRIO MIXTUS (CELLVIBRIO MIXTUS)MANNOSIDASE
2B
(A)
(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONEnon-polymer161.21Chemie (IFL)
3C, D, E
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
4F
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
5G
(A)
waterwater18.0528Chemie (HOH)
Sequence modifications
A: 1 - 1 (PDB: 1UZ4)
A: 433 - 440 (PDB: 1UZ4)
A: 2 - 432 (UniProt: Q6QT42)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight50230.7
Non-Polymers*Number of molecules5
Total formula weight533.5
All*Total formula weight50764.2
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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