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1UXT

Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+)polymer50154218.41UniProt (O57693)
Pfam (PF00171)
THERMOPROTEUS TENAX
2B
(A)
1-O-phosphono-alpha-D-glucopyranosenon-polymer260.11Chemie (G1P)
3C
(A)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.41Chemie (NAD)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5E
(A)
waterwater18.0268Chemie (HOH)
Sequence modifications
A: 1 - 501 (UniProt: O57693)
PDBExternal DatabaseDetails
Phe 378Leu 378engineered mutation
Leu 402Ser 402conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight54218.4
Non-Polymers*Number of molecules3
Total formula weight946.6
All*Total formula weight55164.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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