1UXT
Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008886 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity |
| A | 0008911 | molecular_function | lactaldehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0043878 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0120533 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (non-phosphorylating) activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UXR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UXU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11842090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UXT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11842090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15288789","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UXV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a4s |
| Chain | Residue | Details |
| A | CYS297 | |
| A | GLU263 | |
| A | ASN168 |
