1UXJ
Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | MALATE DEHYDROGENASE | polymer | 309 | 32747.8 | 2 | UniProt (P80040) Pfam (PF00056) Pfam (PF02866) | CHLOROFLEXUS AURANTIACUS | |
| 2 | C, K (A, C) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, F, G, L... (A, C) | CADMIUM ION | non-polymer | 112.4 | 9 | Chemie (CD) | |||
| 4 | H, O (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I, J, P (A, C) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 6 | S, T (A, C) | water | water | 18.0 | 640 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 309 (UniProt: P80040)
| PDB | External Database | Details |
|---|---|---|
| Lys 165 | Glu 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65495.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2478.4 | |
| All* | Total formula weight | 67974.0 |
