1UW4

The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	UPF3X	polymer	91	10902.3	2	UniProt (Q9BZI7) Pfam (PF03467) In PDB	HOMO SAPIENS (HUMAN)	RNA PROCESSING PROTEIN, UPF3B
2	B, D	REGULATOR OF NONSENSE TRANSCRIPTS 2	polymer	248	29278.0	2	UniProt (Q9HAU5) Pfam (PF02854) In PDB	HOMO SAPIENS (HUMAN)	UPF2
3	B, D	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
4		water	water		18.0	314	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80360.7
Non-Polymers*	Number of molecules	2
	Total formula weight	156.3
All*	Total formula weight	80517.0

*Water molecules are not included.