1UVQ
Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN | polymer | 197 | 22275.8 | 1 | UniProt (P01907) Pfam (PF00993) Pfam (PF07654) UniProt (by SIFTS) (E9PMV2) | HOMO SAPIENS (HUMAN) | QA1*0602, DQ(5) ALPHA CHAIN, DC-1 ALPHA CHAIN |
| 2 | B (B) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN | polymer | 198 | 23029.7 | 1 | UniProt (P03992) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01920) | HOMO SAPIENS (HUMAN) | DQB1*0602, DQB1*0602 BETA CHAIN, DQ(5), DC-1 |
| 3 | C (C) | OREXIN | polymer | 33 | 3104.4 | 1 | UniProt (O43612) | HOMO SAPIENS (HUMAN) | HCRT, HYPOCRETIN-1, HCRT1, OREXIN-B, HYPOCRETIN-2, HCRT2 |
| 4 | D (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 5 | E (A) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
| 6 | F, G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | H (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | I (B) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 9 | J, K, L (A, B, C) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A: 1 - 196 (UniProt: P01907)
A: 197 - 197 (PDB: 1UVQ)
B: 3 - 198 (UniProt: P03992)
B: 199 - 200 (PDB: 1UVQ)
C: -4 - 0 (PDB: 1UVQ)
C: 13 - 28 (PDB: 1UVQ)
C: 1 - 12 (UniProt: O43612)
A: 197 - 197 (PDB: 1UVQ)
B: 3 - 198 (UniProt: P03992)
B: 199 - 200 (PDB: 1UVQ)
C: -4 - 0 (PDB: 1UVQ)
C: 13 - 28 (PDB: 1UVQ)
C: 1 - 12 (UniProt: O43612)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48409.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 642.9 | |
| All* | Total formula weight | 49785.5 |
