1UKH
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 8 isoform 4 | polymer | 369 | 42588.2 | 1 | UniProt (P45983) Pfam (PF00069) | Homo sapiens (human) | JNK1 |
| 2 | B (B) | 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1 | polymer | 11 | 1345.6 | 1 | UniProt (Q9WVI9) | JIP1 | |
| 3 | C, D (A, B) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: 1 - 363 (UniProt: P45983)
| PDB | External Database | Details |
|---|---|---|
| His 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43933.8 | |
| All* | Total formula weight | 43933.8 |
