1UHL
Crystal structure of the LXRalfa-RXRbeta LBD heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Retinoic acid receptor RXR-beta | polymer | 236 | 26224.2 | 1 | UniProt (P28702) Pfam (PF00104) In PDB | Homo sapiens (human) | Retinoid X receptor |
| 2 | B | Oxysterols receptor LXR-alpha | polymer | 242 | 28092.2 | 1 | UniProt (Q13133) Pfam (PF00104) In PDB | Homo sapiens (human) | Liver X receptor alpha, Nuclear orphan receptor LXR-alpha |
| 3 | C, D | 10-mer peptide from Nuclear receptor coactivator 2 | polymer | 10 | 1276.5 | 2 | UniProt (Q15596) In PDB | NCoA-2, Transcriptional intermediary factor 2 | |
| 4 | A | (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID | non-polymer | 268.4 | 1 | Chemie (MEI) | |||
| 5 | B | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE | non-polymer | 481.3 | 1 | Chemie (444) | |||
| 6 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
B: 207 - 447 (UniProt: Q13133)
| PDB | External Database | Details |
|---|---|---|
| Met 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56869.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 749.7 | |
| All* | Total formula weight | 57619.2 |
