1UDT
Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 324 | 37530.3 | 1 | UniProt (O76074) Pfam (PF00233) | Homo sapiens (human) | Phosphodiesterase 5 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | non-polymer | 474.6 | 1 | Chemie (VIA) | |||
| 5 | E (A) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37530.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 564.3 | |
| All* | Total formula weight | 38094.6 |
