1U9W
Crystal Structure of the Cysteine Protease Human Cathepsin K in Complex with the Covalent Inhibitor NVP-ABI491
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin K | polymer | 217 | 23737.7 | 1 | UniProt (P43235) Pfam (PF00112) | Homo sapiens (human) | Cathepsin O, Cathepsin X, Cathepsin O2 |
| 2 | B (A) | 9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE | non-polymer | 428.5 | 1 | Chemie (IHI) | |||
| 3 | C (A) | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23737.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 428.5 | |
| All* | Total formula weight | 24166.2 |
