1U3H
Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, F (A, E) | T-cell receptor alpha-chain | polymer | 110 | 12290.6 | 2 | UniProt (Q5R1B3) Pfam (PF07686) | Mus musculus (house mouse) | |
2 | B, G (B, F) | Mouse TCRVbeta 172.10, extracellular variable domain | polymer | 111 | 12112.2 | 2 | UniProt (P04213) Pfam (PF07686) | Mus musculus (house mouse) | |
3 | C, H (C, G) | H-2 class II histocompatibility antigen, A-U alpha chain | polymer | 182 | 20670.0 | 2 | UniProt (P14438) Pfam (PF00993) Pfam (PF07654) | Mus musculus (house mouse) | |
4 | D, I (D, H) | H-2 class II histocompatibility antigen, A-U beta chain | polymer | 189 | 22495.2 | 2 | UniProt (P06344) Pfam (PF00969) Pfam (PF07654) | Mus musculus (house mouse) | |
5 | E, J (P, I) | Myelin basic protein (MBP)-peptide | polymer | 12 | 1295.4 | 2 | UniProt (by SIFTS) (P04370) | synthetic construct | |
6 | K, L, M, N, O... (A, B, C, D, P...) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
C, G: 4 - 181 (UniProt: P14438)
PDB | External Database | Details |
---|---|---|
Ile 1 | - | cloning artifact |
Glu 2 | - | cloning artifact |
Ala 3 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 137726.8 | |
All* | Total formula weight | 137726.8 |